Dim Key1 As Microsoft.Win32.RegistryKey
        Key1 = My.Computer.Registry.CurrentUser   '返回当前用户键
        Dim Key2 As Microsoft.Win32.RegistryKey
     
        Key2 = Key1.OpenSubKey("northsnow")       '返回当前用户键下的northsnow键
        If Not Key2 Is Nothing Then
            Key1.DeleteSubKey("northsnow")  '如果键不存在就创建它
        End If
 3,创建或读取注册表项

Dim Key1 As Microsoft.Win32.RegistryKey
        Key1 = My.Computer.Registry.CurrentUser   '返回当前用户键
        Dim Key2 As Microsoft.Win32.RegistryKey
        Key2 = Key1.OpenSubKey("northsnow", True)       '返回当前用户键下的northsnow键,如果想创建项，必须指定第二个参数为true
        If Key2 Is Nothing Then
            Key2 = Key1.CreateSubKey("northsnow")  '如果键不存在就创建它
        End If

        '创建项，如果不存在就创建，如果存在则覆盖
        Key2.SetValue("name", "塞北的雪")
        Key2.SetValue("sex", True)
        Key2.SetValue("age", 30)

        '返回项值
        Dim sb As New System.Text.StringBuilder
        sb.AppendLine(Key2.GetValue("name"))
        sb.AppendLine(Key2.GetValue("sex"))
        sb.AppendLine(Key2.GetValue("age"))
        MsgBox(sb.ToString)

        '查验某个项是否存在
        If (Key2.GetValue("name")) Is Nothing Then
            MsgBox("no")
        Else
            MsgBox("yes")
        End If

        If (Key2.GetValue("name2")) Is Nothing Then
            MsgBox("no")
        Else
            MsgBox("yes")
        End If

'输出
'  塞北的雪
'True
'30
'yes
'no
4,遍历注册表

这个也非常简单，在窗体上放一个按钮和两个文本框，添加如下的代码

  Dim sb As New System.Text.StringBuilder  '返回遍历结果
    Dim sb2 As New System.Text.StringBuilder  '返回读取出错的注册表键
    Private Sub Button3_Click()Sub Button3_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button3.Click
        Dim Key1 As Microsoft.Win32.RegistryKey
        Key1 = My.Computer.Registry.CurrentUser   '返回当前用户键
        If Not Key1 Is Nothing Then
            sb.AppendLine(Key1.Name)
            readValue(Key1)
            readReg(Key1)
        End If
        Me.TextBox1.Text = sb.ToString
        Me.TextBox2.Text = sb2.ToString
    End Sub
    '遍历注册表键树
    Private Sub readReg()Sub readReg(ByVal r As Microsoft.Win32.RegistryKey)
        If r.SubKeyCount > 0 Then
            Dim keyName() As String
            Dim keyTemp As Microsoft.Win32.RegistryKey
            keyName = r.GetSubKeyNames
            Dim i As Integer
            For i = 0 To keyName.GetLength(0) - 1
                Try
                    sb.AppendLine(keyName(i))
                    keyTemp = r.OpenSubKey(keyName(i), True)
                    readValue(keyTemp)
                    readReg(keyTemp)
                Catch ex As Exception
                    sb2.AppendLine(keyName(i))
                End Try
            Next
        End If
    End Sub
    '遍历某键下的项
    Private Sub readValue()Sub readValue(ByVal r As Microsoft.Win32.RegistryKey)
        If r.ValueCount > 0 Then
            Dim valueName() As String
            Dim i As Integer
            valueName = r.GetValueNames
            For i = 0 To valueName.GetLength(0) - 1
                sb.AppendLine("####")
                sb.Append(r.Name)
                sb.Append("----")
                sb.Append(r.GetValue(valueName(i)).ToString)
            Next
        End If
    End Sub